ArticleOpen heart2025
First year after surgery is the optimal period to define early prosthetic valve endocarditis: a cohort study.
Article in Open heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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17 authors.
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Abstract
backgroundThe definition of early prosthetic valve endocarditis (PVE) remains controversial. This study aims to refine the definition of early PVE by analysing data from the Spanish endocarditis registry (Spanish Collaboration on Endocarditis).
methodsFrom 2008 to 2022, 1305 consecutive cases of PVE were included. The objective was to identify the time period that best defined early PVE by comparing the frequency of cases due to nosocomial micro-organisms and the frequency of intracardiac complications. For this purpose, the periods most frequently considered in the literature were selected: the first 4, 6 or 12 months after surgery. Each of these three periods was compared with a period immediately thereafter.
resultsMost cases of PVE diagnosed within the first year were caused by nosocomial pathogens, such as coagulase-negative staphylococci (CoNS) (236 cases, 49.3 %) and
conclusionsWe consider that the first year after surgery is the most appropriate period for defining early PVE. Our results question whether cases diagnosed in the first 6 months after surgery constitute cases of early EVP and the need for valve replacement, as postulated by European guidelines.
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