Evidence map›Paper›PMID 40571318›Full record

ArticleCancer genomics & proteomics2025

Contribution of MRE11, RAD50, and NBS1 Genotypes to Bladder Cancer Susceptibility.

Cheng-Hsi Liao, Wen-Shin Chang, Hou-Yu Shih, Yun-Chi Wang, Che-Lun Hsu, Shu-Yu Chang, Chao-Hsiang Chang, Wen-Chi Chen, DA-Tian Bau, Chia-Wen Tsai

Abstract read
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Article in Cancer genomics & proteomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cheng-Hsi Liao *Taichung Armed Forces General Hospital, Taichung, Taiwan, R.O.C.
Wen-Shin Chang *Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Hou-Yu Shih *Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yun-Chi WangTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Che-Lun HsuGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Shu-Yu ChangTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chao-Hsiang ChangSchool of Medicine, China Medical University, Taichung, Taiwan, R.O.C.
Wen-Chi ChenSchool of Medicine, China Medical University, Taichung, Taiwan, R.O.C.
DA-Tian BauTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; 013280@tool.caaumed.org.tw 017891@tool.caaumed.org.tw.
Chia-Wen TsaiTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; 013280@tool.caaumed.org.tw 017891@tool.caaumed.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimGenome instability is a hallmark of cancer, often accelerated by defects in DNA damage responses. MRE11-RAD50-NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA damage; however, there is limited literature on the involvement of MATERIALS AND

methodsWe genotyped 14 single nucleotide polymorphisms (SNPs) in

resultsAmong these SNPs, only

conclusion

Indexed as

Cell Cycle ProteinsDNA-Binding ProteinsDNA Repair EnzymesGenetic Predisposition to DiseaseMRE11 Homologue ProteinNuclear ProteinsUrinary Bladder NeoplasmsAcid Anhydride HydrolasesAgedCase-Control StudiesFemaleGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideAcid Anhydride HydrolasesCell Cycle ProteinsDNA-Binding ProteinsDNA Repair EnzymesMRE11 Homologue ProteinMRE11 protein, humanNBN protein, humanNuclear ProteinsRAD50 protein, humanBladder Cancerdouble strand breaksgenotypepolymorphismTaiwan

Identifiers

PMID40571318
PMCPMC12216569

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.