Evidence map›Paper›PMID 40571316›Full record

ArticleCancer genomics & proteomics2025

Elevated

Shin-Nosuke Yamashita, Yoshiatsu Tanaka, Shajedul Islam, Honoka Kotake, Maki Tanaka, Takao Kitagawa, Kazuhiro Tokuda, Durga Paudel, Sarita Giri, Tohru Ohta and 3 more

Abstract read
In one paragraph

Article in Cancer genomics & proteomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Cancer genomics & proteomics
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shin-Nosuke Yamashita *Advanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Yoshiatsu Tanaka *Advanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Shajedul Islam *Advanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Honoka KotakeSchool of Medical Technology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Maki TanakaSchool of Medical Technology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Takao KitagawaAdvanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Kazuhiro TokudaGraduate School of Health and Welfare, Yamaguchi Prefectural University, Yamaguchi, Japan.
Durga PaudelAdvanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Sarita GiriAdvanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Tohru OhtaAdvanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Fumiya HaradaDivision of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Hiroki NagayasuDivision of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Yasuhiro KuramitsuAdvanced Research Promotion Centre, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan; climates@hoku-iryo-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimUveal melanoma (UVM) is the most prevalent primary intraocular malignancy, accounting for 3-5% of all melanomas. Despite its rarity, particularly in Japan (~2 cases per 100,000 individuals annually), UVM exhibits highly aggressive behavior, with nearly 50% of patients developing distant metastases. Once metastasized, the prognosis remains dismal, with a median survival of only 4-5 months. Identifying prognostic biomarkers and potential therapeutic targets is imperative to improve clinical outcomes. Stanniocalcin-1 (STC-1) is a glycoprotein hormone implicated in calcium and phosphate homeostasis. Recent studies have linked MATERIALS AND

methodsTo elucidate the clinical relevance of

results

conclusionThese findings suggest that

Indexed as

Biomarkers, TumorGlycoproteinsMelanomaUveal NeoplasmsFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedPrognosisTumor MicroenvironmentUveal MelanomaBiomarkers, TumorGlycoproteinsteleocalcinKaplan–Meier survival plotretinoblastomasingle cell RNA-seqStanniocalcin-1TCGAuveal melanoma

Identifiers

PMID40571316
PMCPMC12216570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.