Evidence map›Paper›PMID 40570262›Full record

SynthesisPLoS computational biology2025

On the usage of artificial intelligence in leprosy care: A systematic literature review.

Hilson Gomes Vilar de Andrade, Elisson da Silva Rocha, Kayo H de Carvalho Monteiro, Cleber Matos de Morais, Danielle Christine Moura Dos Santos, Dimas Cassimiro Nascimento, Raphael A Dourado, Theo Lynn, Patricia Takako Endo

Abstract readSystematic Review
In one paragraph

Synthesis in PLoS computational biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hilson Gomes Vilar de AndradePrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.ORCID 0000-0001-9739-7910
Elisson da Silva RochaPrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.
Kayo H de Carvalho MonteiroPrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.
Cleber Matos de MoraisPrograma de Pós-Graduação em Comunicação, Universidade Federal da Paraíba (UFPB), João Pessoa, Brazil.
Danielle Christine Moura Dos SantosPrograma Associado de Pós-Graduação em Enfermagem (PAPGenf), Universidade de Pernambuco (UPE), Recife, Brazil.
Dimas Cassimiro NascimentoPrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.
Raphael A DouradoPrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.
Theo LynnBusiness School, Dublin City University (DCU), Dublin, Ireland.
Patricia Takako EndoPrograma de Pós-Graduação em Engenharia da Computação (PPGEC), Universidade de Pernambuco (UPE), Recife, Brazil.ORCID 0000-0002-9163-5583

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Ministério da Saúde (MS)Secretaria de CiênciaTecnologia e Inovação e do Complexo Econômico-Industrial da Saúde (SECTICS)
6 · The paper itself

Abstract

Leprosy, or Hansen's disease, is a Neglected Tropical Disease (NTD) caused by Mycobacterium leprae that mainly affects the skin and peripheral nerves, causing neuropathy to varying degrees. It can result in physical disabilities and functional loss and is particularly prevalent amongst the most vulnerable populations in tropical and subtropical regions worldwide. The persistent stigma and social exclusion associated with leprosy complicate eradication efforts exacerbate the wider challenges faced by NTDs in sourcing the necessary resources and attention for control and elimination. The introduction of Multidrug Therapy (MDT) significantly lowers the global disease burden. Despite this breakthrough in the treatment of leprosy, over 200,000 new leprosy cases are reported annually across more than 120 countries, emphasizing the need for ongoing detection and management efforts. Artificial Intelligence (AI) has the potential to transform leprosy care by accelerating early detection, improving accurate diagnosis, and enabling predictive modeling to improve the quality for those affected. The potential of AI to provide information to assist healthcare professionals in interventions that reduce the risk of disability, and consequently stigma, particularly in endemic regions, presents a promising path to reducing the incidence of leprosy and improving integration social status of patients. This systematic literature review (SLR) examines the state of the art in research on the use of AI for leprosy care. From an initial 657 works from six scientific databases (ACM Digital Library, IEEE Xplore, PubMed, Scopus, Science Direct and Springer), only 30 relevant works were identified, after analysis of three independent reviewers. We have excluded works due duplication, couldn't be retrieved and quality assessment. Results show that current research is focused primarily on the identification of symptoms using image based classification using three main techniques, neural networks, convolutional neural networks, and support vector machines; a small number of studies focus on other thematic areas of leprosy care. A comprehensive systematic approach to research on the application of AI to leprosy care can make a meaningful contribution to a leprosy-free world and help deliver on the promise of the Sustainable Development Goals (SDG).

Indexed as

Artificial IntelligenceLeprosyComputational BiologyHumans

Identifiers

PMID40570262
PMCPMC12225980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.