Evidence map›Paper›PMID 40570186›Full record

ReviewBiochemical Society transactions2025

Understanding carboxysomes to enhance carbon fixation in crops.

Nghiem Dinh Nguyen, Loraine M Rourke, Alexandra Cleaver, Joseph Brock, Benedict M Long, Dean G Price

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nghiem Dinh NguyenBiochemical Science and Biochemistry Division, Research School of Biology, 134 Linnaeus Way, Australian National University, Acton, ACT 2601, Australia.ORCID 0000-0002-4322-4755
Loraine M RourkePlant Science Division, Research School of Biology, 134 Linnaeus Way, Australian National University, Acton, ACT 2601, Australia.ORCID 0000-0002-2600-8073
Alexandra CleaverBiochemical Science and Biochemistry Division, Research School of Biology, 134 Linnaeus Way, Australian National University, Acton, ACT 2601, Australia.ORCID 0009-0003-0557-5938
Joseph BrockBiochemical Science and Biochemistry Division, Research School of Biology, 134 Linnaeus Way, Australian National University, Acton, ACT 2601, Australia.ORCID 0000-0003-3476-9478
Benedict M LongARC Centre of Excellence in Synthetic Biology, Sydney, NSW, Australia.ORCID 0000-0002-4616-2967
Dean G PricePlant Science Division, Research School of Biology, 134 Linnaeus Way, Australian National University, Acton, ACT 2601, Australia.ORCID 0000-0001-5906-4912

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carboxysomes are bacterial microcompartments that enhance photosynthetic CO2 fixation by encapsulating ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) within a high-CO2 environment. Their modular, self-assembling nature makes them attractive for synthetic biology applications, particularly their transplantation alongside functional bicarbonate (HCO3-) transporters into plant chloroplasts to achieve improved photosynthetic efficiency. Recent advances have deepened our understanding of carboxysome biogenesis, Rubisco organisation and shell function. However, key questions remain, including the precise shell mechanistic action, which is critical for functional integration into new hosts. Addressing these questions, as well as identifying suitable bicarbonate transporters and fine-tuning expression levels, will be essential to utilising carboxysomes and the cyanobacterial CO2-concentrating mechanism for enhanced photosynthetic efficiency in crops.

Indexed as

Carbon CycleCrops, AgriculturalOrganellesBicarbonatesCarbon DioxideChloroplastsCyanobacteriaPhotosynthesisRibulose-Bisphosphate CarboxylaseBicarbonatesCarbon DioxideRibulose-Bisphosphate Carboxylasecarbon fixationcyanobacteriaphotosynthesisRubiscosynthetic biology

Identifiers

PMID40570186
PMCPMC12312397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.