Evidence map›Paper›PMID 40569922›Full record

ArticlePloS one2025

The cytological analysis of crossing over in armadillos supports the existence of a phylogenetic component of recombination rates in mammals.

Luis Francisco Rossi, María Inés Pigozzi

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luis Francisco RossiInstituto de Investigaciones Biomédicas, INBIOMED (Universidad de Buenos Aires- CONICET), Buenos Aires, Argentina.
María Inés PigozziInstituto de Investigaciones Biomédicas, INBIOMED (Universidad de Buenos Aires- CONICET), Buenos Aires, Argentina.ORCID 0000-0002-3105-0073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals rates of recombination are well predicted by the phylogenetic relationship between species, with lower recombination rates in more basal clades. In this regard, there is currently insufficient evidence for Xenarthra, one of the earliest branches of eutherian mammals. Here we estimated the average recombination rates in four species of armadillos (Cingulata, Xenarthra) using immunodetection of the protein MLH1, a reporter of reciprocal recombination, in pachytene. The recombination rates of the examined species are strikingly similar; despite the fact that they split more than 40 million years ago, suggesting that this may be a conserved trait in other Xenarthra. We provide evidence that armadillos have lower recombination rates than the average for eutherian mammals, and that they approach those of rodents more closely than those of early mammalian clades like Afrotheria.

Indexed as

ArmadillosMammalsPhylogenyRecombination, GeneticAnimalsMutL Protein Homolog 1MutL Protein Homolog 1

Identifiers

PMID40569922
PMCPMC12200783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.