Evidence map›Paper›PMID 40569886›Full record

ArticleThe FEBS journal2025

Potential cytotoxicity of truncated slow skeletal muscle troponin T (ssTnT) in a loss of function TNNT1 myopathy mouse model.

Han-Zhong Feng, Kevin A Strauss, Jian-Ping Jin

Abstract read
In one paragraph

Article in The FEBS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Han-Zhong FengDepartment of Physiology and Biophysics, University of Illinois at Chicago, IL, USA.
Kevin A StraussClinic for Special Children, Gordonville, PA, USA.
Jian-Ping JinDepartment of Physiology and Biophysics, University of Illinois at Chicago, IL, USA.ORCID https://orcid.org/0000-0001-9932-1063

Funding

Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
Targeting Troponin T Regulation to Sustain Cardiac Function in Heart FailureR01HL138007 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2018 to 2026
$2.4M
NHLBI NIH HHS HL127691NHLBI NIH HHS HL138007NHLBI NIH HHS R01 HL127691NHLBI NIH HHS R01 HL138007
6 · The paper itself

Abstract

A nonsense mutation in codon Glu

Indexed as

Muscle, SkeletalMyopathies, NemalineTroponin TAnimalsDisease Models, AnimalGene Knock-In TechniquesHumansMiceMice, KnockoutTroponin TAmish Nemaline Myopathyslow skeletal muscle troponin Tslow type musclestransgenic mice

Identifiers

PMID40569886
PMCPMC12354317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.