Evidence map›Paper›PMID 40569754›Full record

ArticleAntimicrobial agents and chemotherapy2025

EUCAST olorofim MICs for 3,550 Danish mold and dermatophyte isolates from 2020 to 2023.

Joseph Meletiadis, Karin Meinike Jørgensen, Karen Marie Thyssen Astvad, Nissrine Abou-Chakra, Maiken Cavling Arendrup

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph Meletiadis *Unit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0002-8869-1509
Karin Meinike Jørgensen *Unit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0001-8771-5153
Karen Marie Thyssen AstvadUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0002-4651-2904
Nissrine Abou-ChakraUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0009-0002-5451-5379
Maiken Cavling ArendrupUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0002-4747-0144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dihydroorotate dehydrogenase (DHODH) inhibitor olorofim has potent activity against most molds. Recent reports of

Indexed as

Antifungal AgentsArthrodermataceaeFungiPiperazinesPyrimidinesAcetamidesAmphotericin BAspergillusDenmarkDihydroorotate DehydrogenaseDrug Resistance, FungalFusariumHumansItraconazoleMicrobial Sensitivity TestsNitrilesAcetamidesAmphotericin BAntifungal AgentsDihydroorotate DehydrogenaseisavuconazoleItraconazoleNitrilesolorofimPiperazinesposaconazolePyridinesPyrimidinesPyrrolesTerbinafineTriazolesVoriconazoleantifungal agentsantifungal susceptibility testingdermatophyteEUCAST AFSTmoldolorofim

Identifiers

PMID40569754
PMCPMC12326962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.