Evidence map›Paper›PMID 40569572›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2025

Progress on incorporating sex as a biological variable in cardiovascular research.

Merry L Lindsey, Amanda J LeBlanc, Crystal M Ripplinger, Zamaneh Kassiri, Jonathan A Kirk, Petra Kleinbongard, Jason R Carter, Keith R Brunt

Abstract readEditorial
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Merry L LindseyDepartment of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, Tennessee, United States.ORCID 0000-0002-4090-0391
Amanda J LeBlancDepartment of Cardiovascular and Thoracic Surgery and Cardiovascular Innovation Institute, University of Louisville, Louisville, Kentucky, United States.ORCID 0000-0003-2507-1203
Crystal M RipplingerDepartment of Pharmacology, UC Davis School of Medicine, Davis, California, United States.ORCID 0000-0002-9908-4106
Zamaneh KassiriDepartment of Physiology, Cardiovascular Research Center, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-9357-0912
Jonathan A KirkDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Chicago, Illinois, United States.ORCID 0000-0002-5192-2860
Petra KleinbongardInstitute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.ORCID 0000-0003-3576-3772
Jason R CarterRobbins College of Health and Human Sciences, Baylor University, Waco, Texas, United States.ORCID 0000-0001-7350-6537
Keith R BruntDepartment of Pharmacology, Faculty of Medicine, Dalhousie University, Saint John, New Brunswick, Canada.ORCID 0000-0002-5728-8135

Funding

The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
GSK-3β Localizes to the Myofilament and Modifies its Function in Ischemic CardiomyopathyR01HL136737 · NHLBI · UNIVERSITY OF CHICAGO · PI JONATHAN A KIRK · 2017 to 2026
$4.5M
Calcium Regulation in Heart Failure with Preserved versus Reduced Ejection FractionR01HL147570 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CINGOLANI, EUGENIO, GOLDHABER, JOSHUA I · 2019 to 2022
$3.0M
Sex differences in cardiac autonomic remodeling after myocardial infarctionR01HL170626 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Crystal May Ripplinger, Marmar Vaseghi · 2024 to 2026
$2.1M
Short Course In Transferable Skills Training (SHIFT) ProgramR25GM151274 · NIGMS · MEHARRY MEDICAL COLLEGE · PI MERRY L. LINDSEY, Pius N Nde · 2023 to 2026
$1.9M
Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
Reversing Microvascular Dysfunction in Advancing AgeR01AG053585 · NIA · UNIVERSITY OF LOUISVILLE · PI LEBLANC, AMANDA J · 2017 to 2021
$1.7M
Sex-dependent regulation of cardiac cAMP, ECC, and arrhythmia by phosphodiesterasesR01HL179122 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Crystal May Ripplinger, YANG Kevin XIANG · 2025 to 2026
$1.3M
STrengthening Research OpportuNities for Growth at Meharry Medical College (Meharry-STRONG)UC2MD019626 · NIMHD · MEHARRY MEDICAL COLLEGE · PI Taneisha Gillyard Cheairs, PANDU R GANGULA · 2024 to 2026
$1.1M
HHS | National Institutes of Health (NIH) AA024892HHS | National Institutes of Health (NIH) AG053585HHS | National Institutes of Health (NIH) GM151274 and UC2MD019626HHS | National Institutes of Health (NIH) HL111600 and HL170626HHS | National Institutes of Health (NIH) HL136737 and HL147570NHLBI NIH HHS R01 HL111600NHLBI NIH HHS R01 HL136737NHLBI NIH HHS R01 HL147570NHLBI NIH HHS R01 HL170626NHLBI NIH HHS R01 HL179122NIAAA NIH HHS R01 AA024892NIA NIH HHS R01 AG053585NIGMS NIH HHS R25 GM151274NIMHD NIH HHS UC2 MD019626U.S. Department of Veterans Affairs (VA) I01CX002780
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiaccardiovasculareditorialrigor and reproducibilitySABV

Identifiers

PMID40569572
PMCPMC12276984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.