Evidence map›Paper›PMID 40569557›Full record

ArticleAnnals of nuclear medicine2025

The role of dual-tracer PET imaging with ER and HER2 in patients with metastatic breast cancer: a pilot study.

Cheng Liu, Donghui Pan, Yuyun Sun, Xiaoping Xu, Zhongyi Yang, Min Yang, Shaoli Song

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Article in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Cheng Liu *Shanghai Institute of Medical Imaging, Shanghai, 200032, China.
Donghui Pan *NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, No. 20, Qianrong Road, Wuxi, 214063, Jiangsu, China.
Yuyun SunShanghai Institute of Medical Imaging, Shanghai, 200032, China.
Xiaoping XuDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Zhongyi YangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Min YangNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, No. 20, Qianrong Road, Wuxi, 214063, Jiangsu, China. yangmin@jsinm.org.
Shaoli SongShanghai Institute of Medical Imaging, Shanghai, 200032, China. shaoli-song@163.com.ORCID http://orcid.org/0000-0003-2544-7522

Funding

National Natural Science Foundation of China 82302241Shanghai Engineering Research Center of Molecular Imaging Probes Program KY1401-2023Shanghai Municipal Hospital Development Center SHDC220200219Shanghai Scientific and Technological Innovation Program 21XD1431300
6 · The paper itself

Abstract

objectiveAccurate and real-time evaluation of tumor ER and HER2 status is essential for improving the clinical management of patients with metastatic breast cancer (MBC). The purpose of this pilot study was to investigate the value of PET imaging with

methodsFrom January 2021 to September 2023, 17 metastatic breast cancer (MBC) patients underwent

resultsA total of 174 metastatic lesions were detected: 163 (93.7%) showed high

conclusionDual-tracer PET imaging enables noninvasive assessment of ER/HER2 status and intratumoral heterogeneity, providing critical insights for personalized treatment strategies in MBC.

Indexed as

Breast NeoplasmsErb-b2 Receptor Tyrosine KinasesPositron Emission Tomography Computed TomographyReceptors, EstrogenAdultAgedFemaleFluorodeoxyglucose F18Gallium RadioisotopesHumansMiddle AgedNeoplasm MetastasisPilot ProjectsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFluorodeoxyglucose F18Gallium RadioisotopesReceptors, Estrogen18F-FES68 Ga-HER2 affibodyERHER2Metastatic breast cancer

Identifiers

PMID40569557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.