Evidence map›Paper›PMID 40569514›Full record

ArticleDigestive diseases and sciences2025

Hydrogen Sulfide and Methane on Breath Test Correlate with Human Small Intestinal Hydrogen Sulfide Producers and Methanogens.

Maria Jesus Villanueva-Millan, Gabriela Leite, Ruchi Mathur, Ali Rezaie, Cristina Moreno Fajardo, Juliana de Freitas Germano, Walter Morales, Maritza Sanchez, Ignacio Rivera, Gonzalo Parodi and 6 more

Abstract read
In one paragraph

Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Metabolic engineering ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Critical Review: The Past, Present, and Future of Small Intestinal Bacterial Overgrowth (SIBO).JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Modern concepts of small intestinal bacterial overgrowth.Current opinion in gastroenterology · 2025
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maria Jesus Villanueva-MillanMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Gabriela LeiteMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Ruchi MathurMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Ali RezaieMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Cristina Moreno FajardoMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Juliana de Freitas GermanoMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Walter MoralesMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Maritza SanchezMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Ignacio RiveraMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Gonzalo ParodiMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Stacy WeitsmanMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Mohamad RashidMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Ava HosseiniMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Daniel BrimberryMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Gillian M BarlowMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Mark PimentelMedically Associated Science and Technology (MAST) Program, Cedars-Sinai, 770 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA. pimentelm@cshs.org.ORCID http://orcid.org/0000-0002-0619-5115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence indicates that 3 gas breath testing (BT) correlates with stool microbial populations. Breath methane (CH

aimsTo assess relationships between small bowel microbes and breath gases.

methodsREIMAGINE study subjects completed a fasting single-sample BT for CH

resultsDuodenal bacterial profiles differed significantly in subjects with breath H

conclusionThis study demonstrates that duodenal prevalences of H

Indexed as

DuodenumGastrointestinal MicrobiomeHydrogen SulfideIntestine, SmallMethaneAdultAgedBreath TestsFecesFemaleHumansMaleMethanobrevibacterMiddle AgedHydrogen SulfideMethaneBreath testingDuodenumHydrogen sulfideMethaneMethanobrevibacter smithiiMicrobiomeProteus mirabilis

Identifiers

PMID40569514
PMCPMC12627187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.