ArticleJournal of neuro-oncology2025
Posterior parasagittal meningiomas display aggressive features independent of size: a multicenter analysis.
Article in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Current evidence on the cell of origin of meningiomas disputes the arachnoid cap cell dogma.Acta neurochirurgica · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWhile meningioma size is known to correlate with higher histological grade, tumor behavior can vary by anatomical location, suggesting that some meningiomas may exhibit aggressive features early and independent of size. We hypothesized that posterior parasagittal meningiomas possess unique growth characteristics and tested this hypothesis using a retrospective analysis of two independent cohorts.
methodsCohort-A (n = 316) included 123 WHO-grade 2 (GR2) and 193 age and location matched WHO-grade 1 (GR1) meningiomas. Twelve radiological features as well as the histological subtypes, histological grading features and 1p status was evaluated. A volume index (V
resultsTumor volume correlated strongly with GR2 status (p = 3.5 × 10
conclusionsWhile larger meningiomas are generally more aggressive, posterior parasagittal meningiomas display aggressive biology regardless of size. These findings suggest that anatomical location should be incorporated into risk stratification and management decisions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.