ArticleFish physiology and biochemistry2025
Involvement of galanin in reproduction of male tilapia, Oreochromis mossambicus.
Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Galanin(GAL) is recognised for its involvement in various physiological, behavioural, and neuroendocrine functions in vertebrates. Yet, the impact of this peptide on spermatogenesis in fish remains understudied. In this investigation, the administration of 5 µg of GAL receptor agonist (GAL-A) to the tilapia Oreochromis mossambicus did not significantly alter the numbers of different germ cells except for a significant rise in the number of late spermatids compared to the control group. By contrast, treatment with 20 µg of GAL-A caused a significant rise in all germ cell counts and tubule and lumen areas and a significant reduction in the area of interstitium relative to the control group. The numbers of spermatogonia-A, primary and secondary spermatocytes, and early spermatids showed a strong positive association with regard to their respective cyst size. Furthermore, fish administered 20 µg of GAL-A exhibited significant increases in the percentage of GnRH-immunoreactive fibres within the nucleus lateralis tuberis and proximal pars distalis of the pituitary gland, concomitant with significantly higher serum levels of LH, and the intensity of androgen receptor protein expression in the testis when compared to control groups. The in vitro experimental results revealed a significantly increased level of 11-KT in the testis treated with 30 or 300 µM of GAL-A when compared to the control group. Together, these results demonstrate for the first time that GAL-A enhances spermatogenesis and steroidogenesis in the testis. GAL-A may influence these effects through the hypothalamic-pituitary axis and directly at the testicular level in teleosts.
Indexed as
Identifiers
40569307What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.