Evidence map›Paper›PMID 40569172›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025

Aortic valve surgery in adolescents and young adults: analysis of early operative data from the European Congenital Heart Surgeons Association database†.

Alvise Guariento, Claudia Cattapan, Ilias P Doulamis, Zdzislaw Tobota, Bohdan Maruszewski, Mark S Bleiweis, Jeffrey P Jacobs, George E Sarris, Vladimiro Vida

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Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Editorial: What We See Through Cardiac Imaging.Journal of clinical medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alvise GuarientoPediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.ORCID 0000-0002-5495-6919
Claudia CattapanPediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Ilias P DoulamisDepartment of Surgery, Lahey Clinic, Tufts University School of Medicine, Burlington, MA, USA.
Zdzislaw TobotaPediatric Cardiothoracic Surgery, Children's Memorial Health Institute, Warsaw, Poland.
Bohdan MaruszewskiPediatric Cardiothoracic Surgery, Children's Memorial Health Institute, Warsaw, Poland.ORCID 0000-0003-4144-6677
Mark S BleiweisCongenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, USA.
Jeffrey P JacobsCongenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-9916-929X
George E SarrisAthens Heart Surgery Institute, Department of Pediatric Heart Surgery, Mitera Children's Hospital, Athens, Greece.
Vladimiro VidaPediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.ORCID 0000-0002-1829-0259

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAortic valve surgery is a crucial treatment for congenital and acquired aortic disease in adolescents and young adults. This study evaluated outcomes in this group by analysing data from the European Congenital Heart Surgeons Association Congenital Cardiac Database (ECCDB).

methodsA retrospective review included patients aged 10-18 years from the ECCDB who underwent aortic valve surgery between 2013 and 2022. The primary outcome was operative mortality, defined as death within 30 days or during hospitalization. Secondary outcomes included reoperations and postoperative complications. Risk factors for mortality were identified using multivariable logistic regression analysis, and surgical trends were evaluated.

resultsA total of 2129 patients were included, with the majority undergoing valve replacement, followed by valve repair and the Ross procedure. Patients receiving valve replacement were typically older and larger. Over the decade, there was an increase in the use of the Ross procedure. Reoperations were more frequent in the repair group, while postoperative complications were more common in the replacement group. The overall mortality rate was 1.5%. Independent risk factors for mortality included longer cardiopulmonary bypass (CPB) times (odds ratio 1.1, P < 0.001) and annulus enlargement (odds ratio 3.8, P = 0.02). CPB durations exceeding 240 min increased the risk of death. The Ross procedure, particularly in isolated cases without annulus enlargement, was associated with a low mortality rate of 0.4%.

conclusionsAortic valve surgery in adolescents and young adults is complex, with outcomes influenced by CPB time and annulus enlargement. The Ross procedure shows excellent results despite its technical demands.

Indexed as

Aortic ValveHeart Valve Prosthesis ImplantationAdolescentChildDatabases, FactualEuropeFemaleHeart Defects, CongenitalHumansMalePostoperative ComplicationsReoperationRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultAdolescentsAortic valve surgeryDatabaseEuropean Association of Congenital Heart SurgeonsYoung adults

Identifiers

PMID40569172
PMCPMC12208064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.