Evidence map›Paper›PMID 40569148›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells.

Hong Seok Choi, Hyo-Ju Jang, Wan-Young Kim, Sun Ah Park, Euijung Park, Hyun Jun Jung, Tae-Hwan Kwon

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The CTNNB1-TRIM28 complex governs hormone-induced RNA polymerase II dynamics in kidney epithelial cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hong Seok ChoiDepartment of Biochemistry and Cell Biology, Kyungpook National University, Taegu, Korea.ORCID https://orcid.org/0000-0002-2890-0006
Hyo-Ju JangDepartment of Biochemistry and Cell Biology, Kyungpook National University, Taegu, Korea.ORCID https://orcid.org/0009-0000-1420-4491
Wan-Young KimDepartment of Anatomy, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0009-0002-6529-4567
Sun Ah ParkDepartment of Anatomy, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-3027-3259
Euijung ParkEpithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0001-6329-1499
Hyun Jun JungDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-0519-5858
Tae-Hwan KwonDepartment of Biochemistry and Cell Biology, Kyungpook National University, Taegu, Korea.ORCID https://orcid.org/0000-0002-1561-6508

Funding

National Research Foundation of Korea (NRF) RS-2021-NR060094National Research Foundation of Korea (NRF) RS-2023-NR077104
6 · The paper itself

Abstract

Regulation of aquaporin-2 (Aqp2) gene is essential for body water homeostasis. This study investigated how TAZ (a transcriptional coactivator with PDZ-binding motif, Wwtr1) controls vasopressin-driven AQP2 expression. AQP2 expression was studied using collecting duct-specific TAZ-knockout (TAZ

Indexed as

Aquaporin 2Kidney Tubules, CollectingNuclear Receptor Subfamily 4, Group A, Member 1Trans-ActivatorsTranscription FactorsVasopressinsAdaptor Proteins, Signal TransducingAnimalsCell LineGene Expression RegulationMaleMiceMice, KnockoutTranscriptional Coactivator with PDZ-Binding Motif ProteinsAdaptor Proteins, Signal TransducingAqp2 protein, mouseAquaporin 2Nr4a1 protein, mouseNuclear Receptor Subfamily 4, Group A, Member 1Trans-ActivatorsTranscriptional Coactivator with PDZ-Binding Motif ProteinsTranscription FactorsVasopressinsWwtr1 protein, mouseaquaporin‐2NR4A1renal collecting ductTAZtranscription factorvasopressin

Identifiers

PMID40569148
PMCPMC12199786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.