ArticleTranslational vision science & technology2025
In Vivo Stability of Electronic Intraocular Lens Implant for Corneal Blindness.
Article in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Intraocular Micro-LED Epiretinal Projection for Anterior Segment Blindness: Design and Large-Animal Feasibility Study.Bioengineering (Basel, Switzerland) · 2026Article
- Multi-Level Perception Systems in Fusion of Lifeforms: Classification, Challenges and Future Conceptions.Sensors (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Purpose: Electronic technology can add new function to intraocular lenses, including the treatment of corneal blindness. However, it is not known if such an implant can be stably implanted within a living eye over time. This study investigates the long-term stability and safety of an intraocular lens-shaped implant with an embedded electronic microdisplay for potential use in treating corneal blindness. Methods: Five intraocular implants containing a nonfunctional microdisplay and projection optic were surgically implanted into five rabbits after removal of their crystalline lenses. This blocks the natural pathway of light into the eye. The rabbits were monitored over 6 months with photography and biometry to assess the centration and axial stability of the implants. Results: All implants were successfully implanted and remained stable over the 6-month trial. The average distance from the cornea center was 0.868 ± 0.442 mm at 1 month and 0.851 ± 0.591 mm at 6 months. Anterior chamber depth, representing axial stability, was 4.362 ± 0.213 mm at 1 month and 4.351 ± 0.218 mm at 6 months. While posterior capsular opacification and iris adhesions were observed, no major complications occurred. Conclusions: This study is the first to demonstrate long-term stability of an intraocular lens-shaped implant containing an electronic display and optical system. These findings suggest that such implants are viable and safe, supporting their potential as a treatment for corneal blindness and other broader applications. Translational Relevance: Evidence of safety and stability of electronic intraocular lenses in animals paves the way for the study of this emerging field of medical implants in humans.
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Registered trials
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