Evidence map›Paper›PMID 40569097›Full record

ArticleAnimal biotechnology2025

Production of immune receptor knockout chickens via direct

Kristie Jenkins, Daniel Layton, Tamara Gough, Terri O'Neil, Luis Malaver Otega, Ketan Mishra, Kerri Bruce, Kirsten Morris, Terry Wise, Arjun Challagulla and 2 more

Abstract read
In one paragraph

Article in Animal biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristie JenkinsAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Daniel LaytonAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Tamara GoughAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Terri O'NeilAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Luis Malaver OtegaAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Ketan MishraAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Kerri BruceAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Kirsten MorrisAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Terry WiseAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Arjun ChallagullaAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Tim DoranAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.
Andrew BeanAustralian Centre for Disease Preparedness, CSIRO Health and Biosecurity, Geelong, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advancement of genetic engineering in chickens has enabled significant advancement in developmental biology, bioreactors, and disease resilience. The development of CRISPR/Cas9 genome engineering technology has further expanded the potential applications of genetic engineering in poultry. In this study we aimed to evaluate the efficacy of a direct

Indexed as

Animals, Genetically ModifiedChickensGene Knockout TechniquesGerm CellsReceptor, Interferon alpha-betaReceptors, Interleukin-1 Type ITransfectionAnimalsChick EmbryoCRISPR-Cas SystemsFemaleMaleReceptor, Interferon alpha-betaReceptors, Interleukin-1 Type ICRISPR/Cas9Genetic engineeringimmune responseinterferon-α/β receptor 1 (IFNAR1)interleukin 1 receptor, type I (IL1R1)knockout chickens

Identifiers

PMID40569097
PMCPMC12674351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.