Evidence map›Paper›PMID 40569066›Full record

ArticlemBio2025

Polymorphonuclear leukocytes (PMNs) use different, strain-dependent mechanisms to kill the parasite

Frances Mercer, Sandip Kumar Mukherjee, Chi-Lee Ho, Katherine Muratore, Patricia J Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Innate Immune Protection Against HIV in the Female Genital Tract.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frances Mercer *Department of Biological Sciences, California State Polytechnic University Pomona, Pomona, California, USA.
Sandip Kumar Mukherjee *Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, USA.ORCID 0000-0001-9958-5237
Chi-Lee HoDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, USA.
Katherine MuratoreDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, USA.
Patricia J JohnsonDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, USA.ORCID 0000-0003-4472-2702

Funding

Identification of key players mediating internalization of Trichomonas vaginalis extracellular vesicles by host cells and parasite adherence and survival in vivoR01AI148475 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOHNSON, PATRICIA JEAN · 2020 to 2024
$3.3M
Trichomonas vaginalis exosomes: Mediators of host:pathogen interactionsR01AI103182 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOHNSON, PATRICIA JEAN · 2013 to 2017
$2.9M
Determining the subcellular and molecular players in neutrophil trogocytic killing of the sexually-transmitted parasite Trichomonas vaginalisSC3GM135046 · NIGMS · CALIFORNIA STATE POLY U POMONA · PI MERCER, FRANCES · 2020 to 2023
$441k
California State University New Investigator Seed GrantNational Institute of Allergy and Infectious Diseases R01AI148475, R01AI103182National Institute of Allergy and Infectious Diseases SC3GM135046NIAID NIH HHS R01 AI103182NIAID NIH HHS R01 AI148475NIGMS NIH HHS SC3 GM135046
6 · The paper itself

Abstract

The unicellular parasite

Indexed as

NeutrophilsTrichomonas vaginalisCell MembraneExtracellular TrapsFemaleHumansimmune cell killingNETosisneutrophilparasitologytrogocytosis

Identifiers

PMID40569066
PMCPMC12345268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.