ArticleBiomolecules & biomedicine2025
Role of indocyanine green fluorescence and inferior thyroid artery ligation in hypocalcemia after total-thyroidectomy.
Article in Biomolecules & biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative hypocalcemia remains a frequent complication of total thyroidectomy, and identifying intraoperative strategies to prevent it continues to be a key clinical challenge. This retrospective study aims to evaluate the role of indocyanine green (ICG) fluorescence imaging and truncal ligation of the inferior thyroid artery in the development of hypocalcemia following total thyroidectomy. Additionally, it seeks to identify factors associated with or predictive of hypocalcemia measured on postoperative day 1, as well as to determine the prevalence of transient and permanent hypoparathyroidism. The study included 200 patients who underwent total thyroidectomy performed by the same surgical team between January 2023 and March 2024. The surgical technique employed involved ligation of the inferior thyroid artery at its proximal trunk. Serum calcium levels were assessed for all patients during hospitalization, and again at 10 and 30 days post-surgery. Additionally, the relationship between postoperative calcemia and the vascularization of at least one parathyroid gland was evaluated using indocyanine green fluorescence imaging. Hypocalcemia (<8.5 mg/dL) was observed in 81 patients (40.5%) on postoperative day 1. The rate of transient hypoparathyroidism was 31% (62 patients), while permanent postoperative hypoparathyroidism was seen in 2.5% (5 patients). Patients with a positive vascularization index on indocyanine green fluorescence imaging were significantly less likely to experience hypocalcemia (Fisher's exact test, p = 0.0014). The truncal ligation of the inferior thyroid artery did not significantly influence the occurrence of transient or permanent hypoparathyroidism. In conclusion, indocyanine green fluorescence imaging is confirmed as a useful tool for evaluating parathyroid vascularity, although its associated costs should be carefully considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.