ArticleAnnals of the New York Academy of Sciences2025
Real-time measurement of entropy production and export in humans: A step toward entropically informed medicine.
Article in Annals of the New York Academy of Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Real-time measurement of entropy production and export in humans: A step toward entropically informed medicine.Annals of the New York Academy of Sciences · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
Biological organisms are open thermodynamic systems in which internal structure and function arise from a network of heat- and entropy-producing processes, requiring external export of heat and entropy to the environment. System stability, including health and healing, is hypothesized to relate to the mass-normalized rate of entropy production and export, and the capacity to augment both when required. Using a novel methodological framework that allows the continuous measurement of heat fluxes and body temperature, we can estimate internal entropy production and external entropy export in humans during exercise under heat stress. We report the impairment of entropy export leading to entropy accumulation in association with increasing age, reduced fitness, and the presence of diabetes. In all conditions, impairment was also found to be negatively correlated with the VO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.