ReviewEpigenomics2025
Techniques to detect physical interactions between genomic regions.
Review in Epigenomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromatin forms specific intranuclear structures through physical interactions between specific genomic regions mediated by DNA-binding proteins and/or RNAs. Recent efforts have revealed that these genome organizations and dynamics are involved in various functions of genomic DNA, such as regulation of gene expression, DNA replication, cell division, and epigenetic memory, which are mechanisms underlying cell differentiation and disease development. The methods to detect physically interacting chromatin regions and reconstruct 3D genomic organization can be roughly categorized into four types: (i) microscopic observation of visualized intranuclear structures, (ii and iii) sequencing-based methods including proximity ligation-dependent/independent methods, and (iv)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.