ArticleJournal of advanced veterinary and animal research2025
Association of CSN1S1 gene polymorphism on milk components of the Indonesian local PE cross-dairy goats.
Article in Journal of advanced veterinary and animal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to identify Casein Alpha S1 (CSN1S1) gene polymorphism as a biomarker selection for improving the milk quality of Indonesian local PE cross-dairy goats. Materials and Methods: The study utilized 65 does to identify single nucleotide polymorphisms (SNPs) on the target base fragment g.10094 gm.10200 of the CSN1S1 gene. Milk components (MCs) were analyzed using lactoscan and SNPs were identified using Sanger sequencing. Allele and genotype frequencies of the SNPs were determined by MEGA10 and PopGen32 programs. A general linear model was applied to examine the association between each SNP and the content (%) or daily yield (gm/day) of each of the MCs. Results: Eight SNPs were identified, with seven exhibiting dominant homozygous genotype references with genotype frequencies ranging from 0.77 to 0.95. SNP g.10098_C > G significantly affected ( Conclusio: The findings suggest that SNP g.10098_C > G and g.10181_T > A of the CSN1S1 gene may serve as potential biomarkers for selective breeding to enhance milk quality in the local PE cross-dairy goats.
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