ArticleNeuroimage. Reports2021
Brain structure and function changes in ulcerative colitis.
Article in Neuroimage. Reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mapping the neuroimaging landscape of inflammatory bowel disease: a bibliometric analysis and systematic scoping review.Frontiers in neuroscience · 2026Pooled it
- Investigating the Role of Sodium Butyrate in Mouse Models of IBD: A Multimodal Structural and Functional MRI Study.Neural plasticity · 2026Article
- Across Barriers: Blood-Brain and Gut Barrier Signaling in Psychiatric Disorders.Journal of neurochemistry · 2025Review
- Strain-specific responses to dextran sulfate sodium-induced ulcerative colitis in BALB/c and C57BL/6 mice: Comparative analysis of local versus extra-intestinal manifestations.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Current approaches to studying human resting-state function in inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025Article
- Review study of alteration functional activities and networks in ulcerative colitis using resting-state fMRI.Frontiers in neurology · 2025Review
- Experimentally induced colitis impacts myelin development and home-cage behavior in young pigs regardless of supplementation with oral gamma-cyclodextrin-encapsulated tributyrin.Frontiers in neuroscience · 2025Article
- Comparison of volumetric brain analysis in subjects with rheumatoid arthritis and ulcerative colitis.Frontiers in medicine · 2024Article
- Phenome-wide association study of loci harboring de novo tandem repeat mutations in UK Biobank exomes.Nature communications · 2022Article
- Brain structure and function changes in inflammatory bowel disease.Neuroimage. Reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
As the importance of the brain-gut axis in the pathobiology of inflammatory bowel disease continues to evolve, a greater understanding of brain structure and brain functional connectivity (FC) in diseases such as ulcerative colitis (UC) are necessary. In this magnetic resonance imaging (MRI) study, we investigated differences in brain structure and in FC of brain regions in 76 participants with UC and 74 healthy controls (HC). Voxel based morphometry analysis indicated greater grey matter volume in multiple brain regions in UC as compared to HC. Differences in FC between groups were identified in the cerebellar, default mode, visual, and dorsal attention networks. FC differed by sex for the visual and dorsal attention networks. These differences provide evidence that the brain-gut axis is altered in UC and warrant further investigation to determine if they help direct the evolution of UC or if they evolve in response to the presence of UC.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.