Evidence map›Paper›PMID 40568427›Full record

ArticleNeuroimage. Reports2021

No evidence of improvements in inhibitory control with tRNS.

Etienne Sallard, Ethan R Buch, Leonardo G Cohen, Romain Quentin

Abstract read
In one paragraph

Article in Neuroimage. Reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Etienne SallardHuman Cortical Physiology and Neurorehabilitation Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Ethan R BuchHuman Cortical Physiology and Neurorehabilitation Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Leonardo G CohenHuman Cortical Physiology and Neurorehabilitation Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Romain QuentinHuman Cortical Physiology and Neurorehabilitation Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous work suggests that transcranial random noise stimulation (tRNS) over the prefrontal cortex could influence inhibitory control. Nevertheless, the specific neural mechanisms underlying this proposed effect have not been investigated. Here, we aimed at exploring behavioral and neurophysiological effects of tRNS applied over bilateral inferior frontal gyrus (IFG) on inhibitory control performance during a Go/No-go task (GNG). Nineteen participants performed two tRNS sessions (real and sham) in a double-blind crossover design study. Stimulation was applied over the bilateral IFG during 10 min at 1 mA (range: 1/+1). Resting-state MEG activity was recorded before and after tRNS, and performance on a GNG task was tested after tRNS. Behavioral performance during the GNG task was measured by the false alarm rate (FA), the reaction time in Go (RT Go) and No-go trials (RT FA), and the variability in Go responses (individual coefficient of variability, ICV). Neurophysiological impact of tRNS was assessed using global field power and power spectral density analysis of the MEG recording during the GNG task and the resting-state, respectively. tRNS stimulation did not impact inhibitory control performance. MEG analysis showed significant brain modulations during the resting-state with an increase in power spectral amplitude in beta band (20 Hz) following application of real tRNS. Our results suggest that inhibitory control performance is not modulated by tRNS over the IFG. However, we observed significant modulation of oscillatory brain activity during the resting-state, suggesting that tRNS over bilateral IFG specifically targets the dominant frequency band involved in frontal cortical interactions.

Indexed as

Inferior frontal gyrusInhibitory controlMagnetoencephalographyNon-invasive brain stimulation

Identifiers

PMID40568427
PMCPMC12172787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.