Evidence map›Paper›PMID 40568352›Full record

ReviewHemaSphere2025

NK-type large granular lymphocyte leukemia comes of age.

Gianpietro Semenzato, Antonella Teramo, Gregorio Barilà, Giulia Calabretto, Elisa Rampazzo, Elena Buson, Renato Zambello

Abstract readReview
In one paragraph

Review in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Significance of the Microenvironment in T/Nk-Cell Neoplasms.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gianpietro SemenzatoDepartment of Medicine, Hematology Unit University of Padova Padova Italy.ORCID https://orcid.org/0000-0002-6061-4595
Antonella TeramoDepartment of Medicine, Hematology Unit University of Padova Padova Italy.
Gregorio BarilàHematology Unit Ospedale San Bortolo Vicenza Italy.ORCID https://orcid.org/0000-0003-3430-6115
Giulia CalabrettoDepartment of Medicine, Hematology Unit University of Padova Padova Italy.ORCID https://orcid.org/0000-0001-8646-2932
Elisa RampazzoDepartment of Medicine, Hematology Unit University of Padova Padova Italy.
Elena BusonDepartment of Medicine, Hematology Unit University of Padova Padova Italy.
Renato ZambelloDepartment of Medicine, Hematology Unit University of Padova Padova Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NK-large granular lymphocyte leukemia (NK-LGLL) is a lymphoid malignancy driven by constitutive activation of cellular pathways and chronic inflammation, underscoring the central role of the microenvironment in the disease's pathogenesis. Patients with NK-LGLL typically present with an expansion of mature NK cells displaying large granular lymphocyte morphology, a restricted killer Immunoglobulin-like receptor pattern and genetic lesions, including

Identifiers

PMID40568352
PMCPMC12194722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.