ArticleWorld journal of nephrology2025
Renal tubular acidosis: Varied aetiologies and clinical presentations: Three case reports.
Article in World journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Metabolic Acidosis in Patients with Chronic Kidney Disease: Diagnosis, Pathogenesis, and Treatment-A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Distal Renal Tubular Acidosis: A Conundrum of Short Stature, Failure to Thrive, Rickets, and Nephrocalcinosis.Cureus · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
backgroundRenal tubular acidosis (RTA) refers to a group of kidney disorders characterized by defective acid excretion or bicarbonate reabsorption, leading to metabolic acidosis. This case series presents three cases of RTA with distinct etiologies and clinical manifestations. These cases emphasize the necessity of a comprehensive evaluation of RTA, considering both renal and systemic origins. CASE SUMMARY: The first case describes a female patient with osteopetrosis-related RTA, diagnosed with Guibaud-Vainsel syndrome, emphasizing the importance of genetic assessment. The second case delineates RTA secondary to focal segmental glomerulosclerosis, associating tubular dysfunction with glomerular pathology. In the first two cases whole exome sequencing confirmed genetic diagnosis. The third case illuminates RTA as a complication of Graves' disease, highlighting autoimmune implications.
conclusionThese cases underscore the interdisciplinary approach essential in RTA management. Understanding the diverse pathophysiology of RTA aids in tailored therapeutic strategies and improved patient outcomes.
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