Evidence map›Paper›PMID 40568316›Full record

ArticleiScience2025

Alterations in mitochondrial energy metabolites following acute subconcussive head impacts among athletes with and without ADHD.

Gage Ellis, Madeleine K Nowak, William G Kronenberger, Grace O Recht, Osamudiamen Ogbeide, Lillian M Klemsz, Patrick D Quinn, Landon Wilson, Taylor Berryhill, Stephen Barnes and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gage EllisDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Madeleine K NowakDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
William G KronenbergerDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Grace O RechtDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Osamudiamen OgbeideDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Lillian M KlemszDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Patrick D QuinnDepartment of Applied Health Science, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Landon WilsonDepartment of Pharmacology and Toxicology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Taylor BerryhillDepartment of Pharmacology and Toxicology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Stephen BarnesDepartment of Pharmacology and Toxicology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Sharlene D NewmanAlabama Life Research Institute, University of Alabama, Tuscaloosa, AL, USA.
Keisuke KawataDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.

Funding

5500 Q-Trap Mass SpectrometerS10RR027822 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARNES, STEPHEN · 2010 to 2010
$469k
Neuroimaging and blood biomarkers for subconcussive neural stress on ADHDR21NS116548 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI KAWATA, KEISUKE, NEWMAN, SHARLENE D · 2020 to 2020
$436k
NCRR NIH HHS S10 RR027822NINDS NIH HHS R21 NS116548
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is prevalent among contact sports athletes, who may regularly incur repetitive head impacts. This study investigated the effects of acute head impacts on mitochondrial function by analyzing tricarboxylic acid (TCA) cycle metabolites and the potential modulatory role of ADHD. Fifty adult soccer players (ADHD

Indexed as

Earth sciencesEnvironmental scienceLand useRisk assessment

Identifiers

PMID40568316
PMCPMC12192527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.