Evidence map›Paper›PMID 40568266›Full record

ArticleCureus2025

A Case Report of Choroidal Neovascularization Secondary to Angioid Streaks Associated With Beta Thalassemia.

Thanam Tamil Chelvan, Teck Chee Cheng, Jemaima Che Hamzah, Ainal Adlin Naffi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thanam Tamil ChelvanDepartment of Ophthalmology, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Teck Chee ChengDepartment of Ophthalmology, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Jemaima Che HamzahDepartment of Ophthalmology, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Ainal Adlin NaffiDepartment of Ophthalmology, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 58-year-old Malay male with underlying beta thalassemia presented with distorted vision in the right eye for two weeks. On presentation, his visual acuity (VA) was 6/18 OD (right eye) and 6/9 OS (left eye). Fundus examination of the right eye revealed a pink optic disc with peripapillary atrophy and numerous narrow, irregular streaks radiating in a circumferential pattern, along with macular scarring and pigment deposition. The patient was ametropic, with a right eye axial length of 24.72 mm. Optical coherence tomography (OCT) of the macula of the right eye showed subretinal and intraretinal cystic fluid with subretinal fibrosis. Fundus fluorescein angiography demonstrated leakage at 44 seconds, increasing in intensity and size in the early venous phase. The patient was diagnosed with choroidal neovascularization (CNV) secondary to angioid streaks. He was treated with intravitreal ranibizumab, receiving a monthly loading dose for three months, followed by a treat-and-extend regimen up to 16-week intervals. The patient's symptoms resolved after the first injection, and follow-up OCT showed sustained resolution of fluid. Final VA remained 6/18 OD and 6/9 OS, with symptomatic improvement and stability of the condition.

Indexed as

angioid streaksanti-vascular endothelial growth factorbeta thalassemiachoroidal neovascularizationoptical coherence tomography macula

Identifiers

PMID40568266
PMCPMC12187488

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