Evidence map›Paper›PMID 40568252›Full record

ArticleCureus2025

Bacterial or Viral: A Case of Central Nervous System Infection in a Young, Immunocompetent Adult.

Amal Hamieh, Richard Elias, Heba Selim, Joseph Elias

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amal HamiehInternal Medicine, Al Fujairah Hospital, Emirates Health Services, Al Fujairah, ARE.
Richard EliasInternal Medicine, Al Fujairah Hospital, Emirates Health Services, Al Fujairah, ARE.
Heba SelimInternal Medicine, Al Fujairah Hospital, Emirates Health Services, Al Fujairah, ARE.
Joseph EliasInternal Medicine, Al Fujairah Hospital, Emirates Health Services, Al Fujairah, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus (HSV) is a well-documented cause of encephalitis. However, its occurrence alongside concurrent bacterial infections is less commonly reported. Hence, we present this case report, which aims to trace the etiology of acute encephalitis in our patient, a 22-year-old farm attendant, who initially received intravenous and oral antibiotics that may have distorted the lumbar puncture results. The onset of his illness included typical symptoms such as fever, seizures, and altered mental status. The possibility of bacterial co-infection with HSV-1 viral meningoencephalitis, combined with the early administration of antibiotics in our patient, has inspired this case report to highlight the differential diagnosis concerning the microbiological epidemiology of meningoencephalitis, including concurrent bacterial, viral, and fungal infections.

Indexed as

antibiotic usebacterial meningoencephalitisculture negativehsv1 reactivationpcr multiplex negative

Identifiers

PMID40568252
PMCPMC12187976

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.