Evidence map›Paper›PMID 40568111›Full record

ArticlebioRxiv : the preprint server for biology2025

Rapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis.

Alexander D Maitland, Nicholas R Gonzalez, Donna Walther, Francisco Pereira, Michael H Baumann, Grant C Glatfelter

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alexander D MaitlandDesigner Drug Research Unit, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224.
Nicholas R GonzalezDesigner Drug Research Unit, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224.
Donna WaltherDesigner Drug Research Unit, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224.
Francisco PereiraMachine Learning Team, National Institute of Mental Health, Intramural Research Program, Bethesda, Maryland 20814.
Michael H BaumannDesigner Drug Research Unit, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224.
Grant C GlatfelterDesigner Drug Research Unit, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224.

Funding

Development of Dual Dopamine/Serotonin Releasing AgentsZ01DA000522 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ROTHMAN, RICHARD · 2008 to 2008
$598k
Intramural NIH HHS Z01 DA000522
6 · The paper itself

Abstract

Serotonergic psychedelics induce the head twitch response (HTR) in mice, an index of serotonin (5-HT) 2A receptor (5-HT

Indexed as

automationhead twitch responsemachine learningmicepsychedelicsvideo

Identifiers

PMID40568111
PMCPMC12190173

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.