Evidence map›Paper›PMID 40568055›Full record

ReviewJournal of epilepsy research2025

Stigmas in Epilepsy: Systematic Review and Meta-Analysis.

Matheus Henrique Leite E Silva, João Vitor Sabadine Lima, Iza Paula da Silva Lopes, Ana Carolina Valgas da Silva, Isabela Magalhães Lucchi, Gabriela Padovani Oliveira, Luam Anacleto Mandonça Vieira, Guilherme Octávio Martins Bruno, Elisa de Paula França Resende

Abstract readReview
In one paragraph

Review in Journal of epilepsy research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matheus Henrique Leite E SilvaDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
João Vitor Sabadine LimaDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Iza Paula da Silva LopesDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Ana Carolina Valgas da SilvaDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Isabela Magalhães LucchiDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Gabriela Padovani OliveiraDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Luam Anacleto Mandonça VieiraDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Guilherme Octávio Martins BrunoDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Elisa de Paula França ResendeDepartment of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research has disclosed significant associations between stigma suffered by people living with epilepsy (PWE) and psychiatric conditions, especially major depression. These results have practical implication when coupled with the precise regional-and-local prevalences of stigma in its heterogeneous manifestations among PWE. Here we review current research involving stigma in PWE to assess its prevalence and explore psychopathological associations. A systematic review was conducted in PubMed and Scopus to identify clinical trials objectively evaluating prevalence of any type of stigma, enacted and perceived, in PWE, published from database inception to 31 May 2024. A random effects meta-analysis was undertaken, with 6,072 participants, to obtain the meta-prevalence of stigma among PWE. Subgroup analysis moderated by major continent was delineated. A report was obtained from clinical documentation review and adjoined to the evidence generated. From the 105 records identified, 22 studies were eligible for inclusion. The meta-analysis revealed an overall stigma prevalence of 35% (29%; 41%), and subgroups, Africa or Asia (mostly); arbitrarily defined after analysis of geographical study distributions; indicated a prevalence of 40% (34%; 46%) and 28% (21%; 37%), respectively. Significant difference was identified (

Indexed as

EpilepsyMeta-analysisSocial stigma

Identifiers

PMID40568055
PMCPMC12185920

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.