Evidence map›Paper›PMID 40567993›Full record

ArticleFrontiers in public health2025

Baseline medication load and long-term outcomes in COVID-19-hospitalized patients: results of the AUTCOVSTUDY.

Alexandra Graf, Berthold Reichardt, Christine Wagenlechner, Pavla Krotka, Denise Traxler-Weidenauer, Michael Mildner, Julia Mascherbauer, Clemens Aigner, Johann Auer, Ralph Wendt and 1 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexandra Graf *Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Berthold ReichardtAustrian Social Health Insurance Fund, Eisenstadt, Austria.
Christine WagenlechnerCenter for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Pavla KrotkaClinic of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Denise Traxler-WeidenauerClinic of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Michael MildnerClinic of Dermatology, Medical University of Vienna, Vienna, Austria.
Julia MascherbauerDepartment of Internal Medicine 3, University Hospital St. Poelten, St. Poelten, Austria.
Clemens AignerClinic of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Johann AuerDepartment of Internal Medicine I with Cardiology and Intensive Care, St. Josef Hospital Braunau, Braunau am Inn, Austria.
Ralph Wendt *Department of Nephrology, Hospital St. Georg Leipzig, Leipzig, Germany.
Hendrik J Ankersmit *Clinic of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Limited data are available on long-term morbidity and mortality after hospitalization for coronavirus disease 2019 (COVID-19). In this registry-based study, we investigated long-term mortality and morbidity following hospitalization for COVID-19 and examined associations with baseline medication load. Methods: Data were provided by the Austrian Health Insurance Funds on hospitalized COVID-19 patients in 2020 and matched controls. The primary outcome was mortality. Secondary outcomes included mortality conditional on survival of initial COVID-19 hospitalization and re-hospitalization. Results: The median follow-up was 600 days. A total of 22,571 patients aged >18 were hospitalized in Austria in 2020 due to COVID-19. The risk of mortality was significantly higher with polypharmacy. With the exception of the youngest age group (19-40 years), patients receiving antiepileptics, antipsychotics, or iron supplements, erythropoiesis-stimulating agents, vitamin B12, or folic acid in the year before hospitalization were significantly associated with a higher risk of mortality (all Discussion: Antipsychotics and antidepressants appear to be underrecognized in identifying patients at risk for severe outcomes after hospitalization for COVID-19.

Indexed as

COVID-19COVID-19 Drug TreatmentHospitalizationPolypharmacyAdultAgedAustriaFemaleHumansMaleMiddle AgedRegistriesSARS-CoV-2Young Adultall-cause mortalitybaseline medication loadCOVID-19 hospitalizationpolypharmacyreadmissionregistry-based observational study

Identifiers

PMID40567993
PMCPMC12187735

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.