Evidence map›Paper›PMID 40567961›Full record

Observational studyFrontiers in public health2025

Assessing the effects of the COVID-19 pandemic on new ART initiation and viral load access among children and adolescents living with HIV in West Africa: an interrupted time series analysis.

Yao Rodion Konu, Karen Malateste, Sophie Desmonde, Désiré Dahourou, Madeleine Amorissani-Folquet, Mariam Sylla, Caroline Yonaba, Lehila Tossa-Bagnan, Joycelyn Dame, Didier Koumavi Ekouevi and 1 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yao Rodion KonuDépartement de Santé Publique, Université de Lomé, Lomé, Togo.
Karen MalatesteUniversité de Bordeaux, Institut National de la Recherche Médicale (Inserm) UMR 1219, Institut de Recherche pour le Développement (IRD) EMR 271, Bordeaux Population Health Centre, Bordeaux, France.
Sophie DesmondeCentre d'Epidémiologie et Recherche en Santé des POPulations (CERPOP), Inserm - Université Toulouse, Toulouse, France.
Désiré DahourouDépartement de Santé Biomédicale et Publique, Institut de Recherche en Sciences de la Santé, Ouagadougou, Burkina Faso.
Madeleine Amorissani-FolquetCentre Hospitalier Universitaire (CHU) Cocody, Abidjan, Côte d'Ivoire.
Mariam SyllaCHU Gabriel Touré, Bamako, Mali.
Caroline YonabaCHU Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
Lehila Tossa-BagnanCentre National Hospitalier Universitaire, Cotonou, Bénin.
Joycelyn DameDepartement of Child Health, University of Ghana and Korle Bu Teaching Hospital, Accra, Ghana.
Didier Koumavi EkoueviDépartement de Santé Publique, Université de Lomé, Lomé, Togo.
Valériane LeroyCentre d'Epidémiologie et Recherche en Santé des POPulations (CERPOP), Inserm - Université Toulouse, Toulouse, France.

Funding

WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
NIAID NIH HHS U01 AI069919NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

Background: Before the COVID-19 pandemic, the pediatric continuum of HIV care lagged behind that of adults. The present study aimed to describe the effects of the COVID-19 pandemic on access to HIV care among children and adolescents (0-19 years) living with HIV (CALHIV) in five West African countries. Methods: Within this observational multicenter study, we conducted an interrupted time series analysis by including all antiretroviral therapy (ART)-naive CALHIV newly enrolled between 2018 and 2021. Two monthly documented outcomes were analyzed, namely, the number of ART initiators and the number of viral load (VL) tests performed. We fitted Poisson segmented regression models to estimate immediate changes at pandemic onset and per-pandemic trends through incidence rate ratios (IRRs) with 95% confidence intervals (CIs). Results: Immediately after the start of the pandemic, the average number of ART initiations decreased by 83.8% in Burkina Faso (IRR: 0.162; [95%CI: 0.043-0.609]) and 70.9% in Ghana (IRR: 0.291 [0.171-0.494]). Similarly, the number of VL tests performed decreased by 51% in Burkina Faso (IRR: 0.409 [0.253-0.662]). There were no significant trends in the number of ART initiations during the pandemic, except in Ghana (IRR: 1.146 [1.073-1.224]). The number of VL tests performed monthly in clinics in Côte d'Ivoire and Ghana decreased during the pandemic. Conclusion: ART initiation and VL testing activities were maintained in the majority of West African pediatric clinics, despite the COVID-19 pandemic and subsequent crisis. HIV care continuum monitoring in CALHIV should be maintained during the postpandemic period to identify and mitigate potential lasting effects.

Indexed as

Anti-HIV AgentsCOVID-19Health Services AccessibilityHIV InfectionsViral LoadAdolescentAfrica, WesternChildChild, PreschoolFemaleHumansInfantInterrupted Time Series AnalysisMalePandemicsSARS-CoV-2Anti-HIV AgentsART initiationCOVID-19 pandemicHIVVL testingWest Africa

Identifiers

PMID40567961
PMCPMC12187821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.