ArticleHealth science reports2025
Effects of Alpha-Lipoic Acid on Glyphosate-Treated Human Granulosa Cells: A Cross-Sectional Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- NADPH oxidases in immunometabolism and disease pathology: mechanistic networks, pollutant triggers, and therapeutic frontiers.Cellular & molecular immunology · 2026Review
- Critical Assessment of Glyphosate and Alpha-Lipoic Acid Effects on Granulosa Cells.Health science reports · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
Backgrounds and Aims: An association between Glyphosate (GLY) exposure and a higher frequency of miscarriage and preterm birth has been shown. To evaluate the effects of alpha-lipoic acid (ALA) on folliculogenesis gene expression and oxidative stress in human GLY-treated granulosa cells (GCs). Methods: GCs were obtained from 46 healthy women who had tubal or male infertility factors. The GCs were cultured and treated with GLY (250 μg mL Results: DNA fragmentation was less pronounced in the ALA-treated and GLY + ALA groups compared to the GLY-treated group. ALA treatment reduced the apoptotic ratio in GLY treatment and the combination of GLY + ALA (5.5% and 19.6% vs. 35.8%), respectively. GLY reduced the fold expression of Conclusion: Exposure to GLY induced apoptosis, and ALA increased the expression of antioxidant genes in GCs. Additionally, ALA can be recommended to reduce the damage caused by oxidants to the female reproductive system.
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Registered trials
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