ArticlePeerJ. Computer science2025
Enhancing knee osteoarthritis detection with AI, image denoising, and optimized classification methods and the importance of physical therapy methods.
Article in PeerJ. Computer science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Artificial Intelligence Empowers Physical Therapy for Older Adults: A Perspective.Health science reports · 2026Article
- Roles of exosomes in immune regulation of osteoarthritis and their applications in inflammation repair.Frontiers in immunology · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is considered one of the most challenging arthritic disorders due to its high disease burden and lack of effective treatment options that can change the course of the disease. Knee osteoarthritis (KOA) reduces people's quality of life and shortens their daily activities. Therefore, early detection of KOA dramatically impacts patients' quality of life. This study developed an artificial intelligence-supported system to detect KOA. In the developed system, firstly, the images in the original dataset were denoised with a Gaussian filter. Then, feature maps were extracted from both the original and Gaussian applied datasets with the DenseNet201 selected from eight different pre-trained models, and these two feature maps were concatenated. In this way, it is aimed to bring together different features of the same image. Then, feature selection was made using the neighborhood component analysis (NCA) method for the developed system to produce more successful results, and the optimized feature map was classified into six different classifiers. As a result, a high accuracy rate of 85% was achieved in the proposed model. This value is promising for the automatic diagnosis of KOA with computer-aided systems. As a result, a high accuracy rate of 85% was achieved in the developed system of the support vector machine (SVM) classifier. The proposed model was more successful than the other models used in the study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.