Evidence map›Paper›PMID 40567493›Full record

ArticleOrganic process research & development2025

Machine Learning-Driven Optimization of Continuous-Flow Photoredox Amine Synthesis.

Perman Jorayev, Sebastian Soritz, Simon Sung, Mohammed I Jeraal, Danilo Russo, Alexandre Barthelme, Frédéric C Toussaint, Matthew J Gaunt, Alexei A Lapkin

Abstract read
In one paragraph

Article in Organic process research & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Developing Sustainable Chemistry with AI.Accounts of chemical research · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Perman JorayevDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, United Kingdom.
Sebastian SoritzDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, United Kingdom.
Simon SungCambridge Centre for Advanced Research and Education in Singapore, CARES Ltd., 1 CREATE Way, CREATE Tower #05-05, Singapore 138602, Singapore.
Mohammed I JeraalCambridge Centre for Advanced Research and Education in Singapore, CARES Ltd., 1 CREATE Way, CREATE Tower #05-05, Singapore 138602, Singapore.
Danilo RussoDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, United Kingdom.ORCID https://orcid.org/0000-0003-1809-7309
Alexandre BarthelmeUCB Pharma S.A. Allée de la Recherche, Brussels 60 1070, Belgium.
Frédéric C ToussaintUCB Pharma S.A. Allée de la Recherche, Brussels 60 1070, Belgium.
Matthew J GauntYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.ORCID https://orcid.org/0000-0002-7214-608X
Alexei A LapkinDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, United Kingdom.ORCID https://orcid.org/0000-0001-7621-0889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoredox catalysis plays an important role in the synthesis of pharmaceutically relevant compounds such as C-(sp

Indexed as

automationBayesian optimizationflow chemistryphotoredox chemistry

Identifiers

PMID40567493
PMCPMC12186674

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.