Evidence map›Paper›PMID 40567480›Full record

ReviewRSC advances2025

Photothermal applications of upconversion nanoparticles.

Masoomeh Amoozadeh, Danial Khorsandi, Amin Farahani, Atefeh Zarepour, Arezoo Khosravi, Siavash Iravani, Ali Zarrabi

Abstract readReview
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Masoomeh AmoozadehDepartment of Chemistry, University of Isfahan Isfahan 81746 Iran.
Danial KhorsandiTerasaki Institute for Biomedical Innovation Woodland Hills CA 91367 USA.
Amin FarahaniCellular & Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences Tehran Iran.
Atefeh ZarepourDepartment of Biology, Faculty of Arts and Sciences, Kocaeli University 41001 İzmit Kocaeli Turkiye.
Arezoo KhosraviDepartment of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Istanbul Okan University Istanbul 34959 Turkiye.
Siavash IravaniIndependent Researcher W Nazar ST, Boostan Ave Isfahan Iran siavashira@gmail.com.ORCID https://orcid.org/0000-0003-3985-7928
Ali ZarrabiDepartment of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University Istanbul 34396 Turkiye alizarrabi@gmail.com.ORCID https://orcid.org/0000-0003-0391-1769

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upconversion nanoparticles (UCNPs) have become a versatile nanoplatform with promising potential in photothermal applications. By efficiently converting near-infrared (NIR) light into heat, UCNPs offer a non-invasive approach to induce hyperthermia in specific target tissues, such as cancer cells, while preserving surrounding healthy cells. The utilization of UCNPs in combination therapies, multifunctional nanosystems, and regenerative medicine applications highlights their versatility and adaptability in addressing complex healthcare challenges. By leveraging the multifunctionality of UCNPs, researchers can develop approaches for disease management, drug delivery, and monitoring, opening the path for more effective and tailored biomedical interventions. However, challenges such as NIR light penetration limitations, biocompatibility considerations, photothermal conversion efficiency optimization, tumor targeting strategies, and clinical translation studies need to be carefully considered and overcome to maximize the efficacy of UCNPs in photothermal applications. We aim to provide an inclusive exploration of the potential applications of UCNPs in photothermal therapy, highlighting their unique properties and versatility in targeted therapeutic interventions. This review explores the photothermal conversion efficiency, tumor-targeting strategies, and future prospects of UCNPs, aiming to highlight the challenges and opportunities in employing these nanoparticles for precise and effective applications in cancer therapy, tissue engineering, and personalized medicine.

Identifiers

PMID40567480
PMCPMC12188523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.