Evidence map›Paper›PMID 40567463›Full record

ArticleRwanda journal of medicine and health sciences2024

Assessment of Dyslipidaemia and Cardiovascular Disease Risk Factors among Type 2 Diabetes Mellitus Patients Attending Kabutare District Hospital, Huye, Rwanda.

Herbert Tendayi Mapira, Joseph Musangwa, Anselme Mugenga, Jessca Umurerwa, Dominique Ufitikirezi, Cuthbert Musarurwa

Abstract read
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Article in Rwanda journal of medicine and health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Herbert Tendayi MapiraBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
Joseph MusangwaBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
Anselme MugengaBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
Jessca UmurerwaBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
Dominique UfitikireziBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
Cuthbert MusarurwaBiomedical Laboratory Sciences, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dyslipidaemia is a major contributing factor to the development of cardiovascular disease (CVD) in type 2 diabetic mellitus (T2DM) patients. People with T2DM are at a significantly high risk of developing dyslipidaemia which in turn is a risk factor for CVD. The objective of this study was to assess the risk factors for CVD in T2DM patients. Methodology: A descriptive cross-sectional study was conducted on 100 T2DM patients consecutively presenting at Kabutare District Hospital, Huye District southern Rwanda. Excluded were patients on lipid lowering drugs and those with chronic renal and liver diseases. Results: The overall prevalence of dyslipidaemia was 79% with hypoalphalipoproteinaemia (47%) being the most common and hypercholesterolaemia (29%) the least frequent. When stratified according to glycaemic control, median diastolic blood pressure was significantly higher (p=0.045) in participants whose median fasting plasma glucose (FPG) was ≥5.6 mmol/L. Median fasting triglycerides (p=0.006) and non-HDL-C (p=0.019) concentrations were significantly lower in euglycaemic participants compared to participants with median FPG ≥5.6 mmol/L. Dysglycaemia was significantly associated with dyslipidaemia status (p=0.001). Conclusion: Effective management and monitoring of dyslipidaemia, particularly among those with poor glycaemic control, is crucial in mitigating CVD risks in this population.

Indexed as

cardiovascular diseasedyslipidaemiaHypoalphalipoproteinaemia and hyperbetalipoproteinaemiatype 2 diabetes mellitus

Identifiers

PMID40567463
PMCPMC12110474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.