Evidence map›Paper›PMID 40567285›Full record

ArticleNeuroimage. Reports2021

Parkinson's disease-related pattern (PDRP) identified using resting-state functional MRI: Validation study.

Andrea Rommal, An Vo, Katharina A Schindlbeck, Andrea Greuel, Marina C Ruppert, Carsten Eggers, David Eidelberg

Abstract read
In one paragraph

Article in Neuroimage. Reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Functional Brain Networks to Evaluate Treatment Responses in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Stereotyped Relationship Between Motor and Cognitive Metabolic Networks in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea RommalCenter for Neurosciences, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
An VoCenter for Neurosciences, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
Katharina A SchindlbeckCenter for Neurosciences, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
Andrea GreuelDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
Marina C RuppertDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
Carsten EggersDepartment of Neurology, University Hospital Giessen and Marburg, Marburg, Germany.
David EidelbergCenter for Neurosciences, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.

Funding

Statistics and Data Management CoreP50NS071675 · NINDS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI EIDELBERG, DAVID · 2010 to 2014
$9.3M
NINDS NIH HHS P50 NS071675
6 · The paper itself

Abstract

Spatial covariance mapping of brain activity has been used increasingly with metabolic imaging to detect and quantify abnormal disease patterns in patient populations. Metabolic topographies such as the Parkinson's disease-related pattern (PDRP), while extensively validated, require access to positron emission tomography (PET) and radiation exposure. Recently, we developed a fully non-invasive approach to identify analogous disease networks with resting-state functional MRI (rs-fMRI) using independent component analysis (ICA) and bootstrap resampling. We designated the original rs-fMRI PD topography as fPDRP

Indexed as

Brain networkIndependent component analysisParkinson's diseaseResting-state functional MRI

Identifiers

PMID40567285
PMCPMC12172760

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.