ArticleStroke2025
Postacute Discharge Destination and Major Adverse Cardiovascular Events Among Patients With Intracerebral Hemorrhage.
Article in Stroke, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies evaluating health system factors associated with major adverse cardiovascular events (MACE) among intracerebral hemorrhage (ICH) survivors are lacking. We evaluate differences in MACE incidence across postacute ICH care settings-inpatient rehabilitation facilities (IRF), home, or skilled nursing facilities (SNF).
methodsUsing data from Florida, New York, Maryland, Washington, and Georgia, we identified adult ICH survivors discharged to home, IRF, or SNF (April 2016-December 2018). Multivariable logistic models, adjusted for sociodemographic factors, treatment intensity, comorbidities, and frailty, estimated adjusted odds ratios (aORs) and 95% CI for the association between discharge disposition (IRF versus home; IRF versus SNF) and MACE (a composite of acute stroke, acute myocardial infarction, systemic embolism, and vascular death), recurrent ICH, acute ischemic stroke, acute myocardial infarction, vascular death, and all-cause mortality within 1 year. Cardiovascular outcomes were ascertained using
resultsAmong 58 591 patients with ICH (mean age [SD], 68.1 [16.0] years; 47.1% female), 17 647 ICH survivors discharged home (46.4%), to IRF (25.5%), or to SNF (28.1%) were included. Within 1 year, 1302 (7.4%) patients experienced MACE, with rates for recurrent ICH, acute ischemic stroke, acute myocardial infarction, vascular death, and mortality at 2.5%, 3.2%, 0.6%, 1.3%, and 3.5%, respectively. In fully adjusted models, patients discharged to IRF had significantly lower odds of MACE (versus home: aOR, 0.84 [CI, 0.71-0.98]; versus SNF: aOR, 0.79 [CI, 0.67-0.93]), with a significant discharge disposition-age interaction (
conclusionsIRF care (versus SNF and home) was associated with lower odds of MACE. Further research is needed to determine specific components of IRF care contributing to better outcomes.
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