Evidence map›Paper›PMID 40567184›Full record

ArticleBiomarkers in medicine2025

The mean corpuscular volume (MCV) is a hematological biomarker associated with COVID-19 mortality risk.

Víctor Bernal-Dolores, José Manuel Reyes-Ruiz, Kim Rodríguez-Relingh, Gustavo Martínez-Mier

Abstract read
In one paragraph

Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Víctor Bernal-DoloresUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.ORCID 0009-0008-0018-3464
José Manuel Reyes-RuizUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.ORCID 0000-0002-2379-8591
Kim Rodríguez-RelinghUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.ORCID 0009-0006-7636-6983
Gustavo Martínez-MierUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.ORCID 0000-0002-2883-9188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to investigate the role of mean corpuscular volume (MCV) as a predictor of mortality due to COVID-19. MATERIALS AND

methodsThis retrospective, single-center, and longitudinal study included 122 patients with COVID-19.

resultsCompared to the survivor's group, the non-survivors had higher MCV (92.13 ± 3.67 fL), neutrophil-to-lymphocyte ratio [NLR] (16.99 [21.31]), platelet-to-lymphocyte ratio [PLR] (350.33 [304.68]), and systemic immune-inflammation index [SII] (3684.92 [4073.25]) levels (

conclusionMCV > 89 fL and PLR > 418.08 at the time of hospital admission were associated with an increased COVID-19 mortality risk.

Indexed as

COVID-19Erythrocyte IndicesAdultAgedBiomarkersFemaleHumansLongitudinal StudiesLymphocytesMaleMiddle AgedNeutrophilsPrognosisRetrospective StudiesSARS-CoV-2BiomarkersbiomarkerCOVID-19hematological markersMean corpuscular volume (MCV)prognostic valueSARS-CoV-2 infection

Identifiers

PMID40567184
PMCPMC12258186

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.