Evidence map›Paper›PMID 40567059›Full record

ArticleJournal of Alzheimer's disease : JAD2025

Estimation of events in cohort studies based on probability of cognitive impairment.

Jiyeon Park, Erin L Abner, Pei Wang, Changrui Liu, Gregory Jicha, Jordan P Harp, Frederick A Schmitt, Richard J Kryscio

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiyeon ParkDepartment of Statistics, University of Kentucky, Lexington, KY, USA.ORCID 0009-0001-2657-610X
Erin L AbnerAlzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-9566-4111
Pei WangDepartment of Applied Statistics and Operations Research, Bowling Green State University, Bowling Green, OH, USA.ORCID 0009-0008-2308-9462
Changrui LiuDepartment of Mathematics and Statistics, The University of Tennessee at Martin, Martin, TN, USA.ORCID 0000-0002-3051-6126
Gregory JichaAlzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.
Jordan P HarpAlzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.
Frederick A SchmittAlzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.ORCID 0000-0003-4315-2488
Richard J KryscioDepartment of Statistics, University of Kentucky, Lexington, KY, USA.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
University of Kentucky Alzheimer's Disease Research CenterP30AG072946 · NIA · UNIVERSITY OF KENTUCKY · PI LINDA J VAN ELDIK · 2021 to 2026
$23.5M
Role of impaired cognitive states & risk factors in conversion to mixed dementiasR01AG038651 · NIA · UNIVERSITY OF KENTUCKY · PI ABNER, ERIN, KRYSCIO, RICHARD J. · 2011 to 2023
$6.1M
Genomic Architecture of a Key Alzheimer's Disease Mimic: CARTSR56AG057191 · NIA · UNIVERSITY OF KENTUCKY · PI FARDO, DAVID WILLIAM · 2019 to 2020
$1.1M
NCATS NIH HHS UL1 TR001998NIA NIH HHS P30 AG072946NIA NIH HHS R01 AG038651NIA NIH HHS R56 AG057191
6 · The paper itself

Abstract

BackgroundDementia and Alzheimer's disease-causing pathologies progress slowly over decades, and participants are recruited cognitively intact, so designing studies to observe enough cases within a feasible timeframe is important.ObjectiveIn this study, we used readily available basic predictors, age, family history, sex, and apolipoprotein E (

Indexed as

Cognitive DysfunctionAgedAged, 80 and overAlzheimer DiseaseApolipoprotein E4Cohort StudiesFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedProbabilityRisk FactorsApolipoprotein E4Alzheimer's diseaseAPOE4cognitive impairmentcohort designcumulative incidence functiondementiaexpected observation timefamily historylongitudinal cohort study

Identifiers

PMID40567059
PMCPMC13628907

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.