Evidence map›Paper›PMID 40566928›Full record

ArticleThe American journal of sports medicine2025

Failure to Achieve the Patient Acceptable Symptom State 2 Years After Anterior Cruciate Ligament Reconstruction Reflects Poor Knee Loading Patterns.

Jade He, Ashley A Williams, Jennifer C Erhart-Hledik, Constance R Chu

Abstract read
In one paragraph

Article in The American journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jade HeDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Ashley A WilliamsDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Jennifer C Erhart-HledikVeterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.
Constance R ChuDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.

Funding

Enhanced Clinical Diagnosis of Early OsteoarthritisR01AR052784 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHU, CONSTANCE R · 2006 to 2015
$4.1M
NIAMS NIH HHS R01 AR052784
6 · The paper itself

Abstract

backgroundClinical outcomes vary after anterior cruciate ligament reconstruction (ACLR), and osteoarthritis (OA) risk remains high. Consequently, early identification is needed of patients who show potentially modifiable loading patterns suggestive of higher risk for worse outcomes and pre-OA. HYPOTHESIS: This study tested the hypothesis that (1) Patient Acceptable Symptom State (PASS) status derived from the Knee injury and Osteoarthritis Outcome Score (KOOS) is associated with knee loading patterns 2 years after ACLR and (2) failure to achieve the PASS reflects worse knee loading mechanics. STUDY

designCross-sectional study; Level of evidence, 4.

methodsFifty-nine participants with unilateral ACLR (mean ± SD, 33 ± 10 years; 33 [56%] females) assessed by gait analysis and KOOS at 2-year follow-up were categorized according to published KOOS PASS thresholds. Independent

resultsAlthough PASS rates for KOOS subscales ranged from 42% to 100%, only 36% of participants achieved the PASS on all 5 KOOS subscales. Patients achieving the PASS on a given KOOS subscale exhibited different loading patterns when compared with those who did not (PASS-no). Specifically, PASS-no for pain and knee-related quality of life showed lower KFM (

conclusionNearly two-thirds of ACLR recipients failed to achieve the PASS on all KOOS subscales 2 years after ACLR. Failure to achieve the PASS was associated with knee loading patterns linked to worse longer-term outcomes and greater OA risk. CLINICAL RELEVANCE: The KOOS PASS criterion is an accessible screening tool for identifying patients in need of further assessment and treatment to improve knee health and reduce OA risk after ACLR.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionKnee JointAdultBiomechanical PhenomenaCross-Sectional StudiesFemaleGait AnalysisHumansMaleOsteoarthritis, KneeWeight-BearingYoung Adultanterior cruciate ligament reconstruction (ACLR)gait analysisPatient Acceptable Symptom State (PASS)pre-osteoarthritis (pre-OA)

Identifiers

PMID40566928
PMCPMC12320907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.