ArticlePlant communications2025
The ESCRT component FYVE4 modulates salt-stress response by strengthening the SOS1-SOS2 interaction in Arabidopsis.
Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Genome-wide analysis of the SOS2 gene family in melon (Cucumis melo L.) and functional characterization of MELO3C010334 in response to salt stress.BMC plant biology · 2026Article
- ESCRTs in plant abiotic stresses.Essays in biochemistry · 2025Review
- Salt Tolerance in Soybean (Plants (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
The plant-specific FYVE-domain-containing protein FYVE4, a component of the endosomal sorting complex required for transport III (ESCRT-III), participates in membrane protein sorting. However, the mechanism by which FYVE4 coordinates plant growth responses to environmental stress remains unclear. In this study, we reveal a novel function of FYVE4 in positively regulating plant salt resistance by modulating the Salt Overly Sensitive (SOS) signaling pathway. FYVE4 enhances SOS1 phosphorylation by promoting SOS1-SOS2 interactions during salt stress. Loss of FYVE4 reduces the SOS1-SOS2 association, leading to decreased SOS1 phosphorylation and increased plant sensitivity to salt stress. Notably, overexpression of SOS1 does not rescue the salt-sensitive phenotype of fyve4-1, whereas SOS2 overexpression does. In summary, our findings highlight the critical role of FYVE4 in promoting SOS1-SOS2 interactions to mitigate salt stress and reveal a previously unrecognized function of FYVE4 in abiotic stress responses, extending beyond its established role in membrane trafficking regulation.
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Registered trials
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