Evidence map›Paper›PMID 40566656›Full record

ArticleClinical & experimental optometry2026

Utility of optometrist referrals for glaucoma evaluation in a young adult population.

Kent Nguyen, Kristy Yoo, Tanner Frediani, Tracy Lang, John Shan, Brian Toy, Benjamin Y Xu

Abstract read
In one paragraph

Article in Clinical & experimental optometry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kent NguyenDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, USA.
Kristy YooKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Tanner FredianiKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Tracy LangKeck School of Medicine, University of Southern California, Los Angeles, CA, USA.
John ShanKaiser Permanente Southern California, Panorama City Medical Center, Panorama City, CA, USA.
Brian ToyDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, USA.
Benjamin Y XuDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-1573-988X

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
Clinical Evaluation and Risk Stratification of Angle Closure Disease Using Quantitative OCTR01EY035677 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Benjamin Y. Xu · 2024 to 2026
$1.4M
Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure DiseaseK23EY029763 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, BENJAMIN Y. · 2019 to 2023
$1.1M
NEI NIH HHS K23 EY029763NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY035677
6 · The paper itself

Abstract

clinical relevanceFew studies have examined the utility of glaucoma referrals among young adults aged 18-40 years, as glaucoma is primarily a disease of the elderly. There are sparse data about prevalence of myopia, which may confound glaucoma diagnosis in this population.

backgroundTo examine the prevalence and characteristics of primary open angle glaucoma (POAG) patients and suspects among young adults aged 18-39 years referred by optometry for in-office evaluation by glaucoma specialists.

methodsEligible participants who were referred for glaucoma evaluation between 1 January 2015 to 31 December 2019 were identified in the electronic medical record database. Study inclusion required glaucoma suspect diagnosis by optometry with subsequent referral and evaluation by a fellowship-trained glaucoma specialist. Diagnoses of glaucoma suspect and POAG by the glaucoma specialists were ascertained through International Classification of Diseases Tenth Revision codes and confirmed through manual chart review. Electronic medical record data were reviewed for age at time of referral, sex, cup-to-disc ratio, intraocular pressure (IOP), central corneal thickness, spherical equivalent refractive error, and family history of glaucoma. Ocular data from one eye of each included patient was selected at random and compared between glaucoma suspects and glaucoma patients.

resultsAmong 660 patients referred by optometrists for glaucoma evaluation, 151 (22.9%) followed up with referrals. Among evaluated patients, 6 (4.0%) were diagnosed with glaucoma. Glaucoma patients tended to have more severe myopia and higher cup-to-disc ratio compared to glaucoma suspects.

conclusionThe utility of referring young adults for glaucoma evaluation was low in this patient population and practice setting, with only one out of 25 evaluations yielding a positive diagnosis and over 75% of referred patients failing to present for evaluation. Evidence-based methods to risk-stratify patients and establish standardised referral guidelines could be beneficial to ensure proper allocation of glaucoma care resources.

Indexed as

GlaucomaGlaucoma, Open-AngleIntraocular PressureOptometristsOptometryReferral and ConsultationAdolescentAdultFemaleHumansMalePrevalenceRetrospective StudiesYoung AdultDiagnosisglaucomaoptometristreferralssuspects

Identifiers

PMID40566656
PMCPMC12354281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.