Evidence map›Paper›PMID 40566571›Full record

ArticleLife (Basel, Switzerland)2025

Ipsilateral Repeated Bout Effect Across Heterologous Muscle Groups: Eccentric Knee Extensor Conditioning Enhances Elbow Flexor Recovery in Young Women.

Fu-Shun Hsu, Chung-Chan Hsieh, Chia-Yu Tang, Chang-Chi Lai, Yu-Jui Li, Yun-Chung Tseng, Szu-Kai Fu

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fu-Shun HsuDepartment of Exercise and Health Sciences, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.
Chung-Chan HsiehDepartment of Exercise and Health Sciences, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.
Chia-Yu TangGraduate Institute of Sports Training, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.ORCID 0009-0009-3276-3436
Chang-Chi LaiDepartment of Exercise and Health Sciences, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.ORCID 0000-0003-0453-1207
Yu-Jui LiDepartment of Recreation and Sports Management, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.
Yun-Chung TsengDepartment of Mathematical Sciences, College of Science, National Chengchi University, Taipei 11605, Taiwan.
Szu-Kai FuDepartment of Exercise and Health Sciences, College of Kinesiology, University of Taipei, Taipei 111036, Taiwan.ORCID 0000-0002-9380-4862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated whether prior eccentric exercise of knee extensors could attenuate muscle damage in ipsilateral elbow flexors, supporting the presence of an ipsilateral repeated bout effect (IL-RBE) across heterogeneous muscle groups. Sixteen young women were randomized into an intervention group (NL/NU) and a control group (C/NU). The NL/NU group performed eccentric knee extensor exercise 14 days before elbow flexor eccentric loading. Compared to the C/NU group, the NL/NU group exhibited an earlier return to baseline in muscle stiffness (D3: NL/NU = 1.14 ± 0.05 vs. Pre = 0.96 ± 0.03 m/s), joint release angle at 30° (D3: NL/NU = 22.79 ± 1.02 vs. Pre = 24.46 ± 0.87°), and joint release angle at 45° (D2: NL/NU = 37.75 ± 1.38 vs. Pre = 38.83 ± 0.87°), indicating a faster recovery trend in these specific neuromuscular and morphological measures. These results suggest that prior remote eccentric loading induces systemic and neuromuscular adaptations, facilitating improved functional recovery. The findings expand IL-RBE applicability to heterologous muscles within the same limb and support its integration into training and rehabilitation protocols.

Indexed as

cross-educationeccentric exerciseflow effectipsilateral transferneuroinflammationpreconditioningproprioceptionrepeated bout effect

Identifiers

PMID40566571
PMCPMC12193861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.