Effects of Remote Ischemic Conditioning on Cardiovascular Responsiveness in Healthy Individuals.

Inga Kiudulaite, Jelena Cesarskaja, Mante Eidininkiene, Zivile Pranskuniene, Andrius Pranskunas

Abstract read

In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Inga KiudulaiteDepartment of Intensive Care Medicine, Lithuanian University of Health Sciences, Eiveniu g.2, 50161 Kaunas, Lithuania.ORCID 0000-0003-2593-0055

Jelena CesarskajaDepartment of Intensive Care Medicine, Lithuanian University of Health Sciences, Eiveniu g.2, 50161 Kaunas, Lithuania.ORCID 0000-0002-8376-3075

Mante EidininkieneDepartment of Intensive Care Medicine, Lithuanian University of Health Sciences, Eiveniu g.2, 50161 Kaunas, Lithuania.

Zivile PranskunieneInstitute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, Sukileliu pr. 13, 50166 Kaunas, Lithuania.

Andrius PranskunasDepartment of Intensive Care Medicine, Lithuanian University of Health Sciences, Eiveniu g.2, 50161 Kaunas, Lithuania.ORCID 0000-0002-9365-9984

Funding

Research Council of Lithuania (LMTLT) S-MIP-23-79

6 · The paper itself

Abstract

The remote ischemic conditioning (RIC)-induced changes in systemic hemodynamics or circulatory reactivity are unclear. Therefore, we aimed to evaluate the effect of a single bout of RIC on the passive leg raising (PLR)-induced cardiovascular response. This prospective study included 36 healthy volunteers (median age: 24 years). Systemic hemodynamic indices were assessed through the following sequential steps: with the participant in a supine position, during the first PLR maneuver, before RIC, after RIC, during the second PLR maneuver, and with the participant in a supine position. The perfusion index (PI) was measured during PLR before and after RIC. We found no significant differences before and after RIC in the proportion of responders during PLR (participants with stroke volume (SV) change ≥ 10%, 61% vs. 47%,

Indexed as

cardiovascular responsepassive leg raisingperipheral perfusionremote ischemic conditioningsystemic hemodynamics

Identifiers

PMID40566496

DOI10.3390/life15060842

PMCPMC12193887

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.