Evidence map›Paper›PMID 40566368›Full record

SynthesisInternational journal of environmental research and public health2025

Occupational Health Effects of Chlorine Spraying in Healthcare Workers: A Systematic Review and Meta-Analysis of Alternative Disinfectants and Application Methods.

Luca Fontana, Luca Stabile, Elisa Caracci, Antoine Chaillon, Kavita U Kothari, Giorgio Buonanno

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Luca FontanaDepartment of Civil and Mechanical Engineering, Università degli Studi di Cassino e del Lazio Meridionale (UNICAS), 03043 Cassino, Italy.ORCID 0000-0002-8614-4114
Luca StabileDepartment of Civil and Mechanical Engineering, Università degli Studi di Cassino e del Lazio Meridionale (UNICAS), 03043 Cassino, Italy.ORCID 0000-0003-2454-0389
Elisa CaracciDepartment of Civil and Mechanical Engineering, Università degli Studi di Cassino e del Lazio Meridionale (UNICAS), 03043 Cassino, Italy.ORCID 0000-0002-4041-2881
Antoine ChaillonCenter for AIDS Research (CFAR), University of California, San Diego, CA 92093, USA.ORCID 0000-0001-9490-3857
Kavita U KothariIndependent Researcher, Kobe 650-0017, Japan.ORCID 0000-0002-0759-5225
Giorgio BuonannoDepartment of Civil and Mechanical Engineering, Università degli Studi di Cassino e del Lazio Meridionale (UNICAS), 03043 Cassino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorine spraying was widely used during filovirus outbreaks, but concerns about occupational health risks led to a shift toward wiping. This systematic review aimed to evaluate the health risks associated with exposure to disinfectants among healthcare workers (HCWs), with a specific focus on chlorine-based products and spraying compared to alternative disinfectants and general disinfection tasks (GDTs). PubMed, Embase, and Scopus were searched from inception to March 2025. Eligible studies included observational or experimental research on HCWs exposed to chemical disinfectants. Two reviewers independently screened studies, assessed the risk of bias using a validated occupational health tool, and evaluated evidence certainty with the GRADE approach. Meta-analyses used fixed- and random-effects models; heterogeneity was assessed with I

Indexed as

ChlorineDisinfectantsHealth PersonnelOccupational ExposureOccupational HealthDisinfectionHumansChlorineDisinfectantsdisinfectantshealth personneloccupational healthrespiratory disorders

Identifiers

PMID40566368
PMCPMC12192869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.