Evidence map›Paper›PMID 40566280›Full record

ArticleInternational journal of environmental research and public health2025

Association Between Blood Benzene Levels and Periodontal Disease in a Nationally Representative Adult U.S. Population.

Basel Hamoud, Meshari Alfailakwi, Hessah Aljalahmah, Fatema Almael, Sarah Alsaeedi, Khaled Saleh, Bushra Ahmad, Hend Alqaderi

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Basel HamoudMinistry of Health, Kuwait City 15462, Kuwait.ORCID 0009-0009-2357-7818
Meshari AlfailakwiMinistry of Health, Kuwait City 15462, Kuwait.ORCID 0009-0008-3098-9039
Hessah AljalahmahMinistry of Health, Kuwait City 15462, Kuwait.
Fatema AlmaelMinistry of Health, Kuwait City 15462, Kuwait.
Sarah AlsaeediMinistry of Health, Kuwait City 15462, Kuwait.
Khaled SalehMinistry of Health, Kuwait City 15462, Kuwait.
Bushra AhmadDepartment of Public Health, School of Dental Medicine, Tufts University, Boston, MA 02111, USA.ORCID 0009-0003-0376-0996
Hend AlqaderiDepartment of Public Health, School of Dental Medicine, Tufts University, Boston, MA 02111, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Benzene, environmental pollutant, is linked to various adverse health effects, but its impact on oral health remains under-explored. This study examines the association between blood benzene levels and periodontitis, a progressive oral inflammatory condition, using a nationally representative sample of U.S. adults. (2) Methods: Cross sectional data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES) were analyzed. Periodontitis was defined per CDC/AAP. Three weighted multivariable logistic regression models determined the association between blood benzene levels and periodontal severity, adjusting for potential confounders. A structural equation modeling (SEM) analysis evaluated cotinine, smoking biomarker, as a mediator in the relationship between benzene and severe periodontitis. (3) Results: The ordinal logistic regression showed a statistically significant association (AOR = 2.0,

Indexed as

BenzeneEnvironmental ExposureEnvironmental PollutantsPeriodontal DiseasesPeriodontitisAdultAgedBiomarkersCotinineCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysUnited StatesBenzeneBiomarkersCotinineEnvironmental PollutantsbenzenebiomarkerscotinineNHANESoral healthperiodontitis

Identifiers

PMID40566280
PMCPMC12192983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.