Evidence map›Paper›PMID 40566128›Full record

ArticleJournal of clinical medicine2025

A Multicentre, Double-Blind, Randomised, Non-Inferiority Trial of a Novel Single-Injection Intra-Articular HMDA-Cross-Linked Hyaluronate Gel for Knee Osteoarthritis.

Kang-Il Kim, Yong In, Hyung-Suk Choi, Ju-Hong Lee, Jae-Ang Sim, Han-Jun Lee, Young-Wan Moon, Oog-Jin Shon, Jong-Keun Seon, Young-Mo Kim and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kang-Il KimDepartment of Orthopaedic Surgery, Center for Joint Diseases and Rheumatism, Kyung Hee University Hospital at Gangdong, 892 Dongnam-ro, Gang-dong-gu, Seoul 05278, Republic of Korea.
Yong InDepartment of Orthopaedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.ORCID 0000-0002-5932-3934
Hyung-Suk ChoiDepartment of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.
Ju-Hong LeeDepartment of Orthopaedic Surgery, Chonbuk National University Hospital, Jeonju 54907, Republic of Korea.
Jae-Ang SimDepartment of Orthopaedic Surgery, Gachon University Gil Hospital, Gil Medical Center, Incheon 21565, Republic of Korea.
Han-Jun LeeDepartment of Orthopaedic Surgery, Chung-Ang University College of Medicine, Seoul 06973, Republic of Korea.
Young-Wan MoonDepartment of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Oog-Jin ShonDepartment of Orthopaedic Surgery, Yeungnam University College of Medicine, Daegu 42415, Republic of Korea.
Jong-Keun SeonDepartment of Orthopaedic Surgery, Chonnam National University Hwasun Hospital, Hwasun-gun 58128, Republic of Korea.ORCID 0000-0002-6450-2339
Young-Mo KimDepartment of Orthopaedic Surgery, Chungnam National University Hospital, Daejeon 35015, Republic of Korea.
Sang-Jun SongDepartment of Orthopaedic Surgery, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Chong-Bum ChangDepartment of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam-si 13620, Republic of Korea.
Hyuk-Soo HanDepartment of Orthopaedic Surgery/Stem Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-1229-8863

Funding

World Class Plus Project Supporting Program (R&D) funded by the Ministry of Trade, Industry and Energy, Republic of Korea P0017160
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hexamethylenediaminehyaluronic acidintra-articular injectionknee osteoarthritistreatment

Identifiers

PMID40566128
PMCPMC12193865

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.